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Gut Microbiome Changes May Drive Disease Progression and Early Hypertension in ADPKD

Gut Microbiome Changes May Drive Disease Progression and Early Hypertension in ADPKD This cross-sectional pilot study published in Kidney360, examined the gut microbiome of 25 patients with autosomal dominant polycystic kidney disease (ADPKD) and 12 matched healthy controls.Using 16S rRNA sequencing and serum toxin analysis, the study found that patients with ADPKD...

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Lower BMI Linked to Slower Progression to Kidney Failure in ADPKD: Insights from the US and Japan

Lower BMI Linked to Slower Progression to Kidney Failure in ADPKD: Insights from the US and Japan NIH National Library of Medicine published a study that examined the relationship between body mass index (BMI) and age at initiation of renal replacement therapy (RRT) in 3,556 patients with autosomal dominant polycystic kidney disease (ADPKD) from two national registries,...

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Long-Term Uranium Exposure in Drinking Water Linked to CKD Risk in Women

Long-Term Uranium Exposure in Drinking Water Linked to CKD Risk in Women In a large prospective study published in  the American Journal of Kidney Diseases AJKD of over 88,000 women from the California Teachers Study, researchers evaluated the effects of long-term exposure to uranium and arsenic in community drinking water on chronic...

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Silent Stones: The Impact of Asymptomatic Kidney Stones on Disease Progression in ADPKD

Silent Stones: The Impact of Asymptomatic Kidney Stones on Disease Progression in ADPKD In a study published in BMC Nephrology, researchers investigated the influence of asymptomatic kidney stones on disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD). This retrospective cohort study followed 195 ADPKD patients, distinguishing between those with nephrolithiasis...

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Elevated Urinary Arsenic and Its Impact on Kidney Health in US Adults

Elevated Urinary Arsenic and Its Impact on Kidney Health in US Adults Investigators in this research published in the Journal of Trace Elements in Medicine and Biology, December 2024, looked at the association between urinary arsenic levels and kidney damage among US adults from 2007 to 2018 using data from NHANES.Employing multivariable...

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